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Invitrogen™ CCBE1 Polyclonal Antibody
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Product Code. 15727391
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Quantity:
100 μL
Unit Size:
100µL
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15727391 100 μL 100µL
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Product Code. 15727391 Supplier Invitrogen™ Supplier No. PA559534

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: CECREGYIRE DDGKTCTRGD KYPNDTGHEK SENMVKAGTC CATCKEFYQM KQTVLQLKQK IALLPNNAAD LGKYITGDKV LASNTYLPGP PG Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 90%.

The gene encoding CCBE1 (Collagen and calcium-binding EGF domain-containing protein 1) is located on chromosome 18 in a region that is frequently found to be deleted in breast and prostate cancers. CCBE1 is a 406 amino acid secreted protein that contains two collagen-like domains and one calcium-binding epidermal growth factor (EGF-like) domain. In general, EGF-like domains include six cysteine residues that are usually involved in disulfide bonds. Calcium-binding EGF-like domains are subject to amino acid substitutions that disrupt their structure or calcium affinity, therefore altering protein function. Downregulation of the gene encoding CCBE1 is observed with high frequency in breast cancer, suggesting that loss of CCBE1 results in changes in cell adhesion and mobility due to its characterization as an extracellular protein. There are three named isoforms of CCBE1 which are produced as a result of alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCBE1
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CCBE1
Gene Accession No. Q6UXH8
Gene Alias 4933426F18Rik; 9430093N24Rik; CCBE1; collagen and calcium binding EGF domains 1; collagen and calcium-binding EGF domain-containing protein 1; FLJ30681; fof; full of fluid protein; Full of fluid protein homolog; HKLLS1; KIAA1983; MGC50861; mKIAA1983; RGD1307670; UNQ1921/PRO4395
Gene Symbols CCBE1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CCBE1. Recombinant protein control fragment (Product #RP-98285).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 147372
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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