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Invitrogen™ CCDC134 Polyclonal Antibody
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Product Code. 15769980
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Quantity:
100 μL
Unit Size:
100µL
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15769980 100 μL 100µL
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Product Code. 15769980 Supplier Invitrogen™ Supplier No. PA552029

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LLALKNLAQL NDIHQQYKIL DVMLKGLFKV LEDSRTVLTA ADVLPDGPFP QDEKLKDAFS HVVENTAFFG DVVLRFPRIV HYYFDHNSNW NLLIRWGISF CNQTGVFNQG PHSPILSLMA QEL Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.

The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. One such protein is CCDC134, a recently identified secretory protein that has been found to inhibit the transcriptional activity of the Elk1 protein. Overexpression CCDC134 also inhibited the phosphorylation of Erk and JNK/SAPK but not p38 MAPK, while specific siRNA against CCDC134 activated Elk1 transcriptional activity and the phosphorylation of Erk and JNK/SAPK, suggesting a potential inhibiting role of CCDC134 in MAPK-mediated Elk1 transcription. CCDC134 is widely expressing in normal adult tissues, tumors, and cell lines.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCDC134
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CCDC134
Gene Accession No. Q9H6E4
Gene Alias 2310042L06Rik; AW208859; Ccdc134; coiled-coil domain containing 134; coiled-coil domain-containing protein 134; dJ821D11.3
Gene Symbols CCDC134
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CCDC134. Recombinant protein control fragment (Product #RP-91496).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79879
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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