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Invitrogen™ CCDC169 Polyclonal Antibody
Description
Immunogen sequence: VKTLLLKEEL DPLKVSCLET LGFSAAGVAG PENRTCLGQK ALWPACLHGS STLAVCQTHL Antigen sequence identity: Mouse 33%; Rat 30%.
Comprising nearly 4% of human DNA, chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
Specifications
Specifications
| Antigen | CCDC169 |
| Applications | Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.05 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | CCDC169 |
| Gene Accession No. | A6NNP5 |
| Gene Alias | A730037C10Rik; C13orf38; CCDC169; coiled-coil domain containing 169; coiled-coil domain-containing protein 169; RP11-251J8.1 |
| Gene Symbols | CCDC169 |
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