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CCDC36 Monoclonal Antibody (OTI2D11), TrueMAB™, OriGene
Description
Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.
Specifications
Specifications
| Antigen | CCDC36 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Monoclonal |
| Clone | OTI2D11 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 1% BSA, 50% glycerol and 0.02% sodium azide |
| Gene | CCDC36 |
| Gene Accession No. | Q8IYA8 |
| Gene Alias | CT74 |
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Product Title
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