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Invitrogen™ CCDC79 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5144158

Product Code. 17998782

  • € 371.00 / 100µg

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Description

Description

CCDC79 Polyclonal Antibody for IHC (P), ELISA

Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA. In the MAJIN-TERB1-TERB2 complex, TERB1 probably mediates association with the shelterin/telosome complex via interaction with TERF1, promoting priming telomeric DNA attachment'. Promotes telomere association with the nuclear envelope and deposition of the SUN-KASH/LINC complex. Also recruits cohesin to telomeres to develop structural rigidity.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CCDC79
Polyclonal
Unconjugated
TERB1
CCDC79; coiled-coil domain containing 79; coiled-coil domain-containing protein 79; telomere repeat binding bouquet formation protein 1; telomere repeats-binding bouquet formation protein 1; TERB1
Rabbit
Protein G
RUO
283847
-20°C or -80°C if preferred
Liquid
ELISA, Immunohistochemistry (Paraffin)
3 mg/mL
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
Q8NA31
TERB1
Recombinant Human Telomere repeats-binding bouquet formation protein 1 protein (301-550AA).
100 μg
Primary
Human
Antibody
IgG
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