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Invitrogen™ CCL5 (RANTES) Monoclonal Antibody (947A1H11), Biotin
Mouse Monoclonal Antibody
Brand: Invitrogen™ AHC6029
This item is not returnable.
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Description
Purity is >95% by SDS-PAGE. This product is recommended as a detection antibody in Sandwich ELISA applications.
CCL5 (RANTES) is a chemokine gene located on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. CCL5, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells, and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. Diseases associated with CCL5 include Human Immunodeficiency Virus Type 1 and Periapical Granuloma.
Specifications
| CCL5 (RANTES) | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 5mg/mL BSA and 0.5mg/mL sodium azide; pH 7.4 | |
| P13501 | |
| CCL5 | |
| Human recombinant RANTES. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 κ |
| ELISA | |
| 947A1H11 | |
| Biotin | |
| CCL5 | |
| beta-chemokine RANTES; CC chemokine; C-C motif chemokine 5; C-C motif chemokine ligand 5; CCL5; chemokine (C-C motif) ligand 5; D17S136E; EoCP; eosinophil chemotactic cytokine; MGC17164; MuRantes; OTTHUMP00000197106; RANTES; RANTES protein; RANTES(3-68); RANTES(4-68); regulated upon activation normal T-cell expressed and secreted; regulated upon activation, normally T-expressed, and presumably secreted; Scya5; SIS δ; SISd; SIS-delta; SISδ; small inducible cytokine A5; small inducible cytokine subfamily A (Cys-Cys), member 5; small-inducible cytokine A5; T cell-specific protein P228; T-cell specific protein p288; T-cell-specific protein RANTES; TCP228; Unknown (protein for MGC:127014) | |
| Mouse | |
| Protein A | |
| RUO | |
| 6352 | |
| 4°C | |
| Liquid |
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