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CCM2 Mouse anti-Human, Clone: OTI2F9, lyophilized, TrueMAB™

Product Code. 17653121
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Quantity:
100 μg
Unit Size:
100µg
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17653121 100 μg 100µg
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Product Code. 17653121 Supplier Origene Technologies Supplier No. CF503414

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Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

Antigen CCM2
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI2F9
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene CCM2
Gene Accession No. Q9BSQ5
Gene Alias C7orf22, OSM, PP10187
Gene Symbols CCM2
Host Species Mouse
Immunogen Full length human recombit protein of human CCM2 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 83605
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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