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Invitrogen™ CCP110 Polyclonal Antibody
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Product Code. 15614258 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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15614258 100 μL 100µL
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Product Code. 15614258 Supplier Invitrogen™ Supplier No. PA558775

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DKPSLNKSNV LLQGASTQAS SMSMPVLASF SKVDIPIRTG HPTVLESNSD FKVIPTFVTE NNVIKSLTGS YAKLPSPEPS MSPKMHRRRS RTSSACHILI NNPINACELS PKGK Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 79%.

Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCP110
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CCP110
Gene Accession No. O43303
Gene Alias 6330503K22Rik; AA415922; AI427129; AW557948; CCP110; centriolar coiled coil protein 110; centriolar coiled coil protein 110kDa; centriolar coiled-coil protein 110; centriolar coiled-coil protein 110kDa; centriolar coiled-coil protein of 110 kDa; Centriolin; centrosomal protein CP110; centrosomal protein of 110 kDa; CEP1; Cep110; CNTRL; CP110; FAN; Kiaa0419; RGD1310509
Gene Symbols CCP110
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CCP110. Recombinant protein control fragment (Product #RP-98222).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9738
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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