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Invitrogen™ CCR7 Polyclonal Antibody
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Goat Polyclonal Antibody

Brand:  Invitrogen™ PA121613

Product Code. 11566412

  • € 644.00 / 50µg

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Description

Description

Recommended positive controls: Mouse spleen. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

CCR7 is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains and functions as a receptor for 6Ckine/SLC (secondary lymphoid-tissue chemokine), CCL19 and CCL21. CCR7 has been shown to be internalized via clathrin-coated pits and the majority recycled back to the plasma membrane. CCR7 is expressed on T cells and can be used to distinguish populations of naive from central and effector memory T cells. CCR7 has been shown to play a role in migration of memory T cells to inflamed tissue. Expression of CCR7 is also found on DC's. During DC maturation CCR7 expression increases and is thought to be involved in a variety of functions: chemotaxis to the lymph node, cellular architecture, rate of endocytosis, survival and maturation.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CCR7
Polyclonal
Unconjugated
Ccr7
BLR2; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; C-C chemokine receptor type 7; C-C CKR-7; C-C motif chemokine receptor 7; CC-CKR-7; CCR7; CCR-7; CD197; CDw197; chemokine (C-C motif) receptor 7; chemokine (C-C) receptor 7; Cmkbr7; EBI1; Ebi1h; EBV-induced G protein-coupled receptor 1; EBV-induced G-protein coupled receptor 1; Epstein-Barr virus induced gene 1; Epstein-Barr virus-induced G-protein coupled receptor 1; EVI1; lymphocyte-specific G protein-coupled peptide receptor; MIP-3 beta receptor
Goat
Antigen affinity chromatography
RUO
1236, 12775
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 0.1% BSA and 0.1% sodium azide
P32248, P47774
Ccr7
Synthetic peptide DPGKPRKNVLVVALLVIFQVC corresponding to amino acids 2-22 of mouse CCR7.
50 μg
Primary
Human, Mouse
Antibody
IgG
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