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Invitrogen™ CD100 Recombinant Human Monoclonal Antibody (5D12)

Human Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA549983
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Description
CD100 Recombinant Monoclonal Antibody for Flow, ELISA
Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100 (also known as semaphorin 4d), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.
Specifications
| CD100 | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4 | |
| O09126, Q92854 | |
| Sema4d | |
| Recombinant Human SEMA4D protein. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG4 |
| ELISA, Flow Cytometry, Neutralization | |
| 5D12 | |
| Unconjugated | |
| Sema4d | |
| A8; BB18; C9orf164; CD100; coll-4; GR3; M-Sema G; M-sema-G; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D; sema J; Sema4d; Semacl2; SEMAJ; semaphorin 4D; semaphorin H; semaphorin-4D; Semaphorin-C-like 2; semaphorin-J; Semcl2 | |
| Human | |
| Affinity chromatography | |
| RUO | |
| 10507, 20354 | |
| -20°C or -80°C if preferred | |
| Liquid |
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