CD107b (LAMP-2) Rat anti-Mouse, PE, Clone: M3/84, eBioscience™
Rat Monoclonal Antibody
Merk: Affymetrix eBioscience 12-5989-83
Overige gegevens : Gewicht : 0.25000kg
BeschrijvingLysosomes are membrane-bound vacuoles which play a critical role in cellular metabolism. These organelles participate in endocytosis, the synthesis and assembly of acid hydrolases, act as sites for digestion of foreign materials and for specialized autolytic cellular processes. Membrane-associated glycoproteins have an important role in normal lysosomal function. Prior to posttranslational modification, Lysosome Associated Membrane Protein 2 (LAMP 2) is an ∽45 kDa polypeptide. Mature, functional LAMP 2 is extensively glycosylated with a variety of different N-linked and O-linked oligosaccharides with a total molecular weight of ∽100-110 kDa. LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|RP23-193O17.2, CD107b, Lamp-2, Lamp-2a, Lamp-2b, Lamp-2c, Mac3|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.