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Description
CD117/c-kit Monoclonal specifically detects CD117/c-kit in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Specifications
| CD117/c-kit | |
| Monoclonal | |
| DyLight 650 | |
| CD117, CD117 antigen, ckit, C-Kit, EC 2.7.10, EC 2.7.10.1, PBT, piebald trait, Proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, SCFRmast/stem cell growth factor receptor, soluble KIT variant 1, Tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein | |
| Mouse | |
| Protein A or G purified | |
| RUO | |
| Primary | |
| This monoclonal antibody recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section. | |
| Store at 4C in the dark. | |
| IgG1 κ |
| ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen) | |
| C117/370 | |
| ELISA, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen | |
| KIT | |
| Recombinant human CD117/c-kit protein (Uniprot: P10721) | |
| 0.1 mL | |
| Cancer, Cellular Markers, Cytokine Research, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Phospho Specific, Protein Kinase, Signal Transduction, Stem Cell Markers, Tyrosine Kinases | |
| 3815 | |
| Human | |
| Purified |
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