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CD119 (IFN gamma Receptor 1) Monoclonal Antibody (2E2), PE, eBioscience™, Invitrogen™

Armenian Hamster Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-1191-80

59.66 EUR valid until 2024-03-29
Use promo code "21615" to get your promotional price.



Additional Details : Weight : 0.25000kg

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Product Code. 15248649

  • € 89.50 / 25µg
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Description

Description

Description: The monoclonal antibody 2E2 recognizes mouse CD119 also known as IFN gamma receptor1. CD119 heterodimerizes with IFN gamma receptor 2 (AF-1) forming the Class II cytokine receptor. The ligand IFN gamma binds IFN gamma receptor 1 subunit but signal transduction transpires via the IFN gamma receptor 2 subunit. The receptor is involved in host defense and expression is broad including B cells, NK cells, macrophages and dendritic cells as well as other non-hematopoietic cell types. Applications Reported: This 2E2 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 2E2 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. In addition, longer incubations appear to help stain the popμLation; therefore we recommend a 60 minute incubation at 2-8°C. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.

This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
Specifications

Specifications

CD119 (IFN gamma Receptor 1)
Monoclonal
0.2 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P15261
IFNGR1
Affinity chromatography
RUO
15979
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
2E2
PE
IFNGR1
antiviral protein, type 2; AVP, type 2; CD119; CD119 antigen; CDw119; Ifgr; IFN-gamma receptor 1; IFN-gammaR; IFN-gamma-R1; IFN-gamma-R-alpha; Ifngr; IFNGR1; IMD27A; IMD27B; immune interferon receptor 1; INF-g receptor; interferon gamma receptor 1; Interferon gamma receptor alpha-chain; interferon-gamma receptor 1; interferon-gamma receptor alpha chain; Nktar
Armenian Hamster
25 μg
Primary
Mouse
Antibody
IgG
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