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Invitrogen™ Ly-108 Monoclonal Antibody (eBio13G3-19D (13G3-19D)), NovaFluor™ Red 685, eBioscience™, Invitrogen™
Description
Ly108, the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6), is expressed on NK cells, B cells, and T cells. Engagement of the Ly108 receptor enhances NK cell activity and increases the expression of IFN-gamma. This receptor plays a role in the inability of NK cells to kill Epstein Barr virus-infected B cells in X-linked lymphoproliferative disease. In Ly108 knock-out mice, CD4+ T cells show a diminished ability to produce IL-4 and exhibit defective neutrophil functions, indicating the importance of Ly108 in immune regulation and cellular function. Overall, Ly108 is crucial for modulating immune responses and maintaining effective immune cell activity.
Specifications
Specifications
| Antigen | Ly-108 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | eBio13G3-19D (13G3-19D) |
| Concentration | 0.1 mg/mL |
| Conjugate | NovaFluor Red 685 |
| Formulation | PBS with 0.09% sodium azide; pH 7.2 |
| Gene | SLAMF6 |
| Gene Accession No. | Q9ET39 |
| Gene Alias | Activating NK receptor; CD352; KAL1; KAL1b; KALI; KALIb; Ly108; Lymphocyte antigen 108; natural killer-, T- and B-cell antigen; NK-T-B-antigen; NTBA; NTB-A; NTBA receptor; RGD1561848; SF2000; SLAM family member 6; Slamf6; UNQ6123/PRO20080 |
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