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Invitrogen™ CD122 Recombinant Rabbit Monoclonal Antibody (6R8P4)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA558185
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Description
Immunogen sequence: AVKNCSHLEC FYNSRANVSC MWSHEEALNV TTCHVHAKSN LRHWNKTCEL TLVRQASWAC NLILGSFPES QSLTSVDLLD INVVCWEEKG WRRVKTCDFH PFDNLRLVAP HSLQVLHIDT QRCNISWKVS QVSHYIEPYL EFEARRRLLG HSWEDASVLS LKQRQQWLFL EMLIPSTSYE VQVRVKAQRN NTGTWSPWSQ PLTFRTRPA.
CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses, primarily expressed in the hematopoietic system and is present in 3 forms. The low affinity form of CD122 is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from CD122. The protein encoded by the CD122 gene represents the beta subunit and is a type I membrane protein. Diseases associate with CD122 protein dysfunction include oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis.
Specifications
| CD122 | |
| Recombinant Monoclonal | |
| 1.38 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3 | |
| P16297 | |
| Il2rb | |
| Recombinant protein (or fragment). | |
| 20 μL | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG |
| ELISA, Immunocytochemistry | |
| 6R8P4 | |
| Unconjugated | |
| Il2rb | |
| CD122; CD122 antigen; high affinity IL-2 receptor beta subunit; high affinity IL-2 receptor subunit beta; IL-15 receptor beta chain; IL15RB; IL15Rbeta; IL-15Rbeta; IL-2 receptor beta chain; IL-2 receptor subunit beta; IL-2/15 receptor-beta; Il-2/15Rbeta; IL-2R subunit beta; IL2RB; IL-2RB; IL2RBC; Il-2Rbeta; interleukin 15 receptor, beta; interleukin 2 receptor subunit beta; interleukin 2 receptor, beta; interleukin 2 receptor, beta chain; Interleukin-15 receptor subunit beta; Interleukin-2 receptor subunit beta; p70; p70-75; p75 | |
| Rabbit | |
| Protein A | |
| RUO | |
| 16185 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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