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Invitrogen™ CD123 Monoclonal Antibody (32703)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA523818
This item is not returnable.
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Description
Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.
IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. IL-3Ra is responsible for the transmission of signal of Interleukin-3. IL-3Ra and IL-3Rb chain heterodimerization is induced by Interleukin-3, which is required for receptor activation but not high affinity binding. IL-3Ra is also reported that IL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus potential targets for novel therapeutic agents.
Specifications
| CD123 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 5% trehalose and No Preservative | |
| P26951 | |
| IL3RA | |
| Sf 21-derived recombinant human IL-3R alpha/CD123 Lys20-Arg305, predicted. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Flow Cytometry, Immunohistochemistry (Paraffin), Neutralization, Western Blot, Immunocytochemistry | |
| 32703 | |
| Unconjugated | |
| IL3RA | |
| CD123; CD123 antigen; CDw123; Cyrl; cytokine receptor-like protein CYRL; hIL-3Ra; Il-3 alpha subunit; IL-3 receptor alpha chain; IL-3 receptor alpha SP2 isoform; IL-3 receptor subunit alpha; IL3R; IL-3R subunit alpha; Il3ra; IL-3RA; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; interleukin 3 receptor subunit alpha; interleukin 3 receptor, alpha; interleukin 3 receptor, alpha (low affinity); interleukin 3 receptor, alpha chain; interleukin-3 receptor class II alpha chain; Interleukin-3 receptor subunit alpha; Sut-1 | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 3563 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
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