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Invitrogen™ CD137 Chimeric Recombinant Rabbit Monoclonal Antibody (LOB12.3)
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Product Code. 17900801
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Quantity:
200 μg
Unit Size:
200µg
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Product Code. Quantity unitSize
17900801 200 μg 200µg
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Product Code. 17900801 Supplier Invitrogen™ Supplier No. MA548147

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Description

Rabbit Recombinant Monoclonal Antibody

Specificity: This antibody binds to mouse 4-1BB (CD137).

CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD137 Chimeric
Applications ELISA, Flow Cytometry, T-Cell Activation, Immunocytochemistry
Classification Recombinant Monoclonal
Clone LOB12.3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene TNFRSF9
Gene Accession No. P20334
Gene Alias 4 1 BB; 41BB; 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK_00183; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; Ly63; receptor protein 4-1BB; s4 1 BB; s4 1BB; s41BB; sCD137; secreted CD137 antigen; soluble 4 1 BB; soluble 4 1BB; soluble 41BB; soluble CD137; T cell antigen ILA; T-cell antigen 4-1BB; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNF receptor superfamily member 9; TNFRSF9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9
Gene Symbols TNFRSF9
Host Species Rabbit
Immunogen This antibody was generated by immunizing rats with recombinant CD137-Fc fusion protein.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21942
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG κ
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