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Invitrogen™ CD144 (VE-cadherin) Monoclonal Antibody (55-7H1)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA528541
This item is not returnable.
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Description
This antibody recognizes a calcium-independent extracellular epitope on CD144 (VE-cadherin, cadherin 5), an adhesion molecule expressed on endothelial cells.
VE-cadherin is a member of the cadherin superfamily that is located in a six-cadherin cluster in a region on the long arm of chromosome 16 and is involved in loss of heterozygosity events in breast and prostate cancer. VE-cadherin protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, VE-cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but the full length sequence of VE-cadherin has not been determined.
Specifications
| CD144 (VE-cadherin) | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 15mM sodium azide; pH 7.4 | |
| P33151 | |
| CDH5 | |
| Human endothelial cells. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 κ |
| Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot, Immunocytochemistry | |
| 55-7H1 | |
| Unconjugated | |
| CDH5 | |
| 7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cadherin-5; cd144 antigen; VE cadherin; Cd144; cd144 antigen; CDH5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD | |
| Mouse | |
| Protein A | |
| RUO | |
| 1003 | |
| 4°C, do not freeze | |
| Liquid |
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