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CD183 (CXCR3), PerCP-Cyanine5.5, clone: CXCR3-173, eBioscience™

Armenian Hamster Monoclonal Antibody

Merk:  Affymetrix eBioscience 45-1831-80

Overige gegevens : Gewicht : 0.25000kg

 Bekijk meerdere types van dit product via de

Produktcode. 15361170

  • € 135.00 / 25 µg


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Beschrijving

Beschrijving

Description: The monoclonal antibody CXCR3-173 recognizes mouse CD183 also known as CXCR3. CD183 is a seven transmembrane G-protein liked chemokine receptor which binds three ligands; CXCL9 (mig), CXCL10 (IP-10)and CXCL11 (ITAC). CD183 as been shown to play a role in CD4 T cell responses to grafts. CXCR3 knockout mice have compromised allograft rejection responses. Expression is found on NK cells, a subset of T lymphocytes and a subset of Tregs as well as preferential expression on Th1-polarized cells. The antibody CXCR3-173 has been shown to affect chemotaxis in response to ligand. The presence of ligand eliminates staining with the antibody. In vivo addition of the antibody delays cardiac and pancreatic islet allograft rejection.Applications Reported: This CXCR3-173 antibody has been reported for use in flow cytometric analysis.Applications Tested: This CXCR3-173 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 488 nm; Emission: 695 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.
Specificatie

Specificatie

CD183
Monoclonal
0.2mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
O88410
CD183 , CKR-L2 , CMKAR3 , GPR9 , IP10 , IP10-R , Mig-R , an
Armenian Hamster
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Flow Cytometry
CXCR3-173
PerCP-Cyanine5.5
Cxcr3
Conjugated
Cxcr3
IgG
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
12766
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For Research Use Only.