missing translation for 'onlineSavingsMsg'
Learn More

CD184 (CXCR4) Mouse anti-Human, Clone: 12G5, eBioscience™

Mouse Monoclonal Antibody

Merk:  Affymetrix eBioscience 14-9999-80

Overige gegevens : Gewicht : 0.01000kg

 Bekijk meerdere types van dit product via de

Produktcode. 15248327

  • € 71.25 / 25 µg


Geschatte verzenddatum
bij leverancier 23-01-2020
Toevoegen aan winkelmandje

Beschrijving

Beschrijving

Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.
Specificatie

Specificatie

CD184 (CXCR4)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P61073
CXC Chemokine Receptor 4, Fusin, LESTR, HUMSTR
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry, Functional Assay, Neutralization
12G5
Unconjugated
CXCR4
Liquid
CXCR4
IgG2a, kappa
25 μg
4° C
Primary
7852
Video's
Documentatie

For Research Use Only.