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CD200 Receptor Mouse anti-Human, Functional Grade, Clone: OX108, eBioscience™
Mouse Monoclonal Antibody
Merk: Affymetrix eBioscience 16-9201-85
Overige gegevens : Gewicht : 0.01000kg
Beschrijving
It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC. CD200R (OX2R) is a receptor for the OX-2 membrane glycoprotein, and both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. CD200R is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. In mouse, CD200R is expressed primarily by peripheral blood monocytes and neutophils but also by other leucocytes including T-lymphocytes and mast cells. Further mouse studies of a gene related to CD200R suggests that the receptor may control myeloid function in a tissue-specific manner. Alternative splicing of CD200R results in multiple transcript variants. Diseases associated with CD200R dysfunction include primary hypertrophic osteoarthropathy.Specificatie
CD200 Receptor | |
Monoclonal | |
1 mg/mL | |
PBS with no preservative; pH 7.2 | |
Q8TD46 | |
CD200R, HCRTR2, MOX2R, OX2R, CD200R1 | |
Mouse | |
Affinity chromatography | |
RUO | |
Antibody | |
Monoclonal | |
Human |
Flow Cytometry, Functional Assay | |
OX108 | |
Functional Grade | |
CD200R1 | |
Liquid | |
CD200R1 | |
IgG1, kappa | |
500 μg | |
4° C | |
Primary | |
131450 |
For Research Use Only.