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CD200 Receptor Mouse anti-Human, Functional Grade, Clone: OX108, eBioscience™

Mouse Monoclonal Antibody

Merk:  Affymetrix eBioscience 16-9201-85

Overige gegevens : Gewicht : 0.01000kg

 Bekijk meerdere types van dit product via de

Produktcode. 15248827

  • € 181.00 / 500 µg


Geschatte verzenddatum
bij leverancier 23-01-2020
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Beschrijving

Beschrijving

It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC. CD200R (OX2R) is a receptor for the OX-2 membrane glycoprotein, and both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. CD200R is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. In mouse, CD200R is expressed primarily by peripheral blood monocytes and neutophils but also by other leucocytes including T-lymphocytes and mast cells. Further mouse studies of a gene related to CD200R suggests that the receptor may control myeloid function in a tissue-specific manner. Alternative splicing of CD200R results in multiple transcript variants. Diseases associated with CD200R dysfunction include primary hypertrophic osteoarthropathy.
Specificatie

Specificatie

CD200 Receptor
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
Q8TD46
CD200R, HCRTR2, MOX2R, OX2R, CD200R1
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry, Functional Assay
OX108
Functional Grade
CD200R1
Liquid
CD200R1
IgG1, kappa
500 μg
4° C
Primary
131450
Video's
Documentatie

For Research Use Only.