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CD21 Antibody (CR2/1952), DyLight 488, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-60733G

Product Code. 18224212

  • € 635.00 / 0.10mL

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Description

Description

CD21 Monoclonal specifically detects CD21 in Human samples. It is validated for ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY
Spécification

Spécification

CD21
Monoclonal
DyLight 488
50mM Sodium Borate with 0.05% Sodium Azide
CR2
Recombinant fragment (around aa 44-196) of human CR2 (CD21) protein (exact sequence is proprietary) (Uniprot: P20023)
0.1 mL
Adaptive Immunity, Apoptosis, B Cell Development and Differentiation Markers, Dendritic Cell Markers, Immunology
Recognizes a protein of 140kDa, which is identified as the complement receptor 2 (CR2)/ CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.
Store at 4°C in the dark.
Immunohistochemistry, Immunohistochemistry (Paraffin)
CR2/1952
Immunohistochemistry, Immunohistochemistry-Paraffin
C3DRSLEB9, CD21, CD21 antigen, Complement C3d receptor, complement component (3d/Epstein Barr virus) receptor 2, complement receptor type 2, Cr2, EBV receptor, Epstein-Barr virus receptor
Mouse
Protein A or G purified
RUO
Primary
Human
IgG1 κ
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