missing translation for 'onlineSavingsMsg'
Learn More

CD22, FITC, clone: eBio4KB128 (4KB128), eBioscience™

Mouse Monoclonal Antibody

Merk:  Affymetrix eBioscience 11-0229-42

Overige gegevens : Gewicht : 0.23750kg

 Bekijk meerdere types van dit product via de

Produktcode. 15546356

  • € 193.00 / 100 tests


Geschatte verzenddatum
bij leverancier 19-09-2018
Toevoegen aan winkelmandje

Beschrijving

Beschrijving

Description: The eBio4KB128 monoclonal antibody recognizes human CD22 (Siglec-2), which is a member of the siglec subgroup of the Ig superfamily. CD22 is a type I transmembrane glycoprotein composed of two polypeptide chains, CD22alpha and CD22beta, of 130 and 140kDa respectively, produced by alternative splicing of the CD22 gene. CD22 is expressed at high levels on mature B cells and B cell lymphomas. The extracellular portion of CD22 contains seven Ig-like domains, some of which are capable of binding ligands with sialic acid moieties expressed on epithelial, endothelial, B and T cells. The intracellular portion of CD22 contains 6 tyrosine residues contained within immunotyrosine-based inhibitory motifs (ITIM) and immunotyrosine-based activation-like motifs, which are phosphorylated upon B-cell receptor engagement, which enables CD22 to participate in the positive and negative regulation of B-cell receptor signaling.Applications Reported: This eBio4KB128 (4KB128) antibody has been reported for use in flow cytometric analysis.Applications Tested: This eBio4KB128 (4KB128) antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.
Specificatie

Specificatie

CD22
Monoclonal
5μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P20273
FLJ22814, MGC130020, SIGLEC-2, SIGLEC2
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
eBio4KB128 (4KB128)
FITC
CD22
Liquid
CD22
IgG1, kappa, kappa
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
933
Video's

For Research Use Only.