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CD223 (LAG-3) Monoclonal Antibody (3DS223H), APC, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

€ 180.00 - € 434.00

Specifications

Antigen CD223 (LAG-3)
Clone 3DS223H
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15331465
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Affymetrix eBioscience
17-2239-41
25 Tests
€ 180.00
25 tests
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Estimated Shipment: 10-04-2024
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15508066
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Affymetrix eBioscience
17-2239-42
100 Tests
€ 434.00
100 tests
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Description

Description

Description: This 3DS223H monoclonal antibody recognizes human CD223 also known as Lymphocyte Activation Gene 3 (LAG-3). LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation. Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells). This 3DS223H antibody will recognize a formaldehyde-fixed epitope. Applications Reported: This 3DS223H antibody has been reported for use in flow cytometric analysis. Applications Tested: This 3DS223H antibody has been pre-titrated and tested by flow cytometric analysis of stimulated normal human peripheral blood cells. This can be used at 5 μL (0.06 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.

CD223 (LAG-3) Monoclonal antibody specifically detects CD223 (LAG-3) in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD223 (LAG-3)
5 μL/Test
Monoclonal
Liquid
RUO
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3
LAG3
IgG1 κ
Affinity chromatography
Antibody
3DS223H
Flow Cytometry
APC
Mouse
Human
P18627
3902
hCD223-FC PFA 4%
Primary
4° C, store in dark, DO NOT FREEZE!
LAG3
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For Research Use Only.