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  6. CD235ab (Glycophorin A/B) Mouse, anti-Human, FITC, Clone: HIR2 (GA-R2), STEMCELL Technologies

CD235ab (Glycophorin A/B) Mouse, anti-Human, FITC, Clone: HIR2 (GA-R2), STEMCELL Technologies

Product Code. p-7218165
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25 μg
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Product Code. Quantity unitSize
17189101 25 μg 25µg
17179101 100 μg 100µg
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Product Code. 17189101 Supplier Stemcell Technologies Supplier No. 60111FI.1

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Description

Mouse Monoclonal Antibody

  • The HIR2 (GA-R2) antibody recognizes an epitope common to the N-terminal region of human CD235a (glycophorin A) and CD235b (glycophorin B), homologous type I sialoglycoproteins of the erythrocyte (red blood cell) membrane that bear the antigenic determinants for the MN and Ss blood groups
  • CD235ab is expressed on early- and late-stage erythroblasts, mature erythrocytes, and erythroid cell lines such as K562 and HEL, but not on other cell types
  • CD235a is abundantly expressed whereas CD235b is a relatively minor membrane component
  • The proteins are believed to provide a large mucin-like surface to erythrocytes that acts to minimize aggregation in the circulation
  • The HIR2 antibody binds with higher affinity to CD235a than CD235b, and agglutinates untreated erythrocytes

Specifications

Antigen CD235ab (Glycophorin A/B)
Applications Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone HIR2 (GA-R2)
Conjugate FITC
Host Species Mouse
Quantity 25 μg
Primary or Secondary Primary
Target Species Human
Isotype IgG2b κ
Cell Type Red Blood Cells
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