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CD27 Mouse, anti-Human, Unconjugated, Clone: O323, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 65132-1-IG-500UG

Product Code. 17271456

  • € 74.00 / 100µg

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Description

Description

CD27 (also known as TNFRSF7) is a type I glycoprotein expressed on some B cells and the majority of T cells, and is a member of the tumor necrosis factor (TNF) receptor family. CD27 is required for generation and long-term maintenance of T cell immunity (PMID: 11062504). It is a receptor for CD70 (CD27L). Ligation of CD27 by CD70 induces strong ubiquitination of TRAF and the activation of both canonical and non-canonical NF-kappaB pathways, as well as the JNK pathway (PMID: 19426224). CD27 may also play a role in apoptosis through association with SIVA1.

Specifications

Specifications

CD27
Monoclonal
0.5 mg/mL
Mouse
Primary
Human
Flow Cytometry
O323
Unconjugated
100 μg
939
Liquid
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