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CD279 (PD-1) Rat anti-Mouse, Clone: RMP1-30, eBioscience™

Rat Monoclonal Antibody

Merk:  Affymetrix eBioscience 14-9981-85

Overige gegevens : Gewicht : 0.01000kg

 Bekijk meerdere types van dit product via de

Produktcode. 15248307

  • € 252.00 / 500 µg


Geschatte verzenddatum
bij leverancier 17-01-2020
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Beschrijving

Beschrijving

The RMP1-30 antibody reacts with mouse PD-1 (programmed death-1), a 55kDa member of the Ig superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease in mice. PD-1 is expressed mainly on activated T and B lymphocytes. Two novel B7 Family members have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. RMP1–30 does not block the binding of either B7-H1-Ig or B7-DC-Ig to PD-1 transfectants.
Specificatie

Specificatie

CD279 (PD-1)
RMP1-30
Unconjugated
Purified
Rat
500μg
Store at 2-8°C.
Monoclonal
Flow Cytometry
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Pdcd1, Programmed cell death protein 1
IgG2b, kappa
RUO
Primary
Murine
Video's
Documentatie

For Research Use Only.