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CD279 (PD-1) Rat anti-Mouse, Clone: RMP1-30, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 14-9981-85
Additional Details : Weight : 0.01000kg
Description
The RMP1-30 antibody reacts with mouse PD-1 (programmed death-1), a 55kDa member of the Ig superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease in mice. PD-1 is expressed mainly on activated T and B lymphocytes. Two novel B7 Family members have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. RMP1–30 does not block the binding of either B7-H1-Ig or B7-DC-Ig to PD-1 transfectants.Specifications
| CD279 (PD-1) | |
| RMP1-30 | |
| Unconjugated | |
| Purified | |
| Rat | |
| 500μg | |
| Store at 2-8°C. | |
| Monoclonal |
| Flow Cytometry | |
| 0.5mg/mL | |
| aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer | |
| Pdcd1, Programmed cell death protein 1 | |
| IgG2b, kappa | |
| RUO | |
| Primary | |
| Murine |
For Research Use Only.