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Invitrogen™ CD2AP Polyclonal Antibody
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Product Code. 15904555
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100 μg
Unit Size:
100µg
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15904555 100 μg 100µg
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Product Code. 15904555 Supplier Invitrogen™ Supplier No. PA578975

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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Jurkat whole cell, human A431 whole cell, human Hela whole cell, human K562 whole cell. IHC: mouse kidney tissue, rat kidney tissue. ICC/IF: Hela cell IP: Jurkat cell. Flow: K56 cell.

This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD2AP
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene CD2AP
Gene Accession No. F1LRS8, Q9JLQ0, Q9Y5K6
Gene Alias adapter protein CMS; AL024079; C78928; Cas ligand with multiple SH3 domains; Cas ligand with multiple Src homology 3 (SH3) domains; CD2 associated protein; Cd2ap; CD2-associated protein; CMS; mesenchyme to epithelium transition protein, SH3 domains; mesenchyme-to-epithelium transition protein with SH3 domains 1; Mets1; METS-1; SH3 domain-containing adapter protein; SH3 domain-containing adaptor protein METS-1
Gene Symbols CD2AP
Host Species Rabbit
Immunogen E. coli-derived human CD2AP recombinant protein (Position: K253-K337).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12488, 23607, 316258
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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