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CD3 Molecular Complex Rat anti-Mouse, FITC, Clone: 17A2, BD

Rat Monoclonal Antibody

€ 116.63 - € 239.09

Specifications

Antigen CD3 Molecular Complex
Clone 17A2
Concentration 0.5mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
15831349
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BD Biosciences
561798
0.1 mg
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€ 117.00
€ 116.63 / Each
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15838038
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BD Biosciences
555274
0.5 mg
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€ 252.00
€ 239.09 / Each
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Description

Description

The 17A2 monoclonal antibody specifically binds to the T-cell receptor-associated CD3 complex that is expressed on many thymocytes and mature T lymphocytes. Plate-bound 17A2 antibody has been reported to induce IL-2 production by cultured T cells in the absence of accessory cells. The binding of the 17A2 antibody to T cells can be blocked by the anti-CD3e mAb 145-2C11. This suggests that the 17A2 antibody recognizes an epitope of the CD3 epsilon chain. In vivo treatment with 17A2 antibody has been reported to partially deplete T lymphocytes and temporarily down-modulates CD3 expression on T cells.

Specifications

Specifications

CD3 Molecular Complex
0.5mg/mL
Monoclonal
Rat
Immunology
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
IgG2b κ
Affinity Purified
17A2
Flow Cytometry
FITC
RUO
Mouse
γδ TCR-positive T-T hybridoma D1
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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