missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Description
Immunogen sequence: TVWCQYESMY KGYNKYWCRG QYDTSCESIV ETKGEEKVER NGRVSIRDHP EALAFTVTMQ NLNEDDAGSY WCKIQTVWVL DSWSRDPSDL VRVYVSPAIT TPRRTTHPAT PPIFLVVNPG RNLSTGEVLT QNSGFR Highest antigen sequence identity to the following orthologs: Mouse - 55%, Rat - 56%.
CD300e is a member of the glycoprotein family of cell surface proteins expressed on myeloid cells. CD300e interacts with the TYRO protein tyrosine kinase-binding protein and is thought to be involved as an activating receptor. CD300e is expressed on mature myeloid dendritic cells and monocytes, and is down regulated on immature dendritic cells. Further, CD300e interacts with DAP-12, which mediates activating signals. The alloreactive response of naïve T cells has been reported to become enhanced by the activation of CD300e. Diseases associated with CD300e dysfunction include tungiasis and lice infestation.
Specifications
Specifications
| Antigen | CD300e |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | CD300E |
| Gene Accession No. | Q496F6 |
| Gene Alias | BC034097; CD300 antigen like family member E; CD300 antigen-like family member E; CD300e; CD300e antigen; CD300e molecule; Cd300le; CLM2; CLM-2; CMRF35A5; CMRF35-A5; CMRF35-like molecule 2; CMRF-35-like molecule-1; Immune receptor expressed on myeloid cells 2; IREM2; IREM-2; PIgR2; PIgR-2; poly-Ig receptor 2; polymeric immunoglobulin receptor 2; TREM5 |
| Gene Symbols | CD300E |
| Show More |
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?
