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  6. CD317 (BST2, PDCA-1) Monoclonal Antibody (26F8), Functional Grade, eBioscience™, Invitrogen™
  7. 17151212

CD317 (BST2, PDCA-1) Monoclonal Antibody (26F8), Functional Grade, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-3179-025

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Product Code. 17151212

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Description

Description

This 26F8 MAb reacts with human CD317 (also known as BST2 and tetherin). CD317 is a 30-36-kDa type II transmembrane protein expressed on B cells and bone marrow stromal cells. Although reports have indicated that CD317 mRNA is detectable in activated T cells, protein expression in primary T cells and macrophages is undetectable. Moreover, certain T cell lines, such as Jurkat, do not express detectable levels of CD317 protein. CD317 has been associated with pre-B cell growth and the terminal differentiation of plasma B cells. More recently, this molecule has been reported to prevent HIV-1 virion release from the surface of infected cells, leading to reuptake and degradation of the virus. This activity is inhibited by the HIV-1 accessory protein Vpu. CD317 has been identified as the ligand for the ILT7 receptor.

CD317 (BST2, PDCA-1) Monoclonal antibody specifically detects CD317 (BST2, PDCA-1) in Human samples. It is validated for Flow Cytometry, Functional Assay, Neutralization
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD317 (BST2, PDCA-1)
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
Q10589
Mouse
25 mg
Primary
Human
Antibody
IgG1 κ
Flow Cytometry, Functional Assay, Neutralization
26F8
Functional Grade
Bst2
2310015I10Rik; Bone marrow stromal antigen 2; bone marrow stromal cell antigen 2; Bst2; BST-2; C87040; CD317; Damp1; DAMP-1; DAMP-1 protein homolog; GREG; HM1.24 antigen; NPC-A-7; PDCA-1; protein DAMP-1; TETHERIN
Affinity chromatography
RUO
684
4° C
Liquid
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