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CD35 Antibody (E11), DyLight 405, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-33080V

Product Code. 18181863

  • € 599.00 / 0.10mL

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Description

Description

CD35 Monoclonal specifically detects CD35 in Human, Monkey, Baboon, Cynomolgus Monkey, Rhesus Macaque samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD35
Monoclonal
DyLight 405
complement component (3b/4b) receptor 1 (Knops blood group), KN
Mouse
215 kDa
0.1 mL
Primary
Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This monoclonal antibody is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This monoclonal antibody is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This monoclonal antibody labels follicular dendritic cells and follicular dendritic cell sarcoma.
Store at 4C in the dark.
IgG1 κ
ELISA
E11
ELISA
CR1
Intact human monocytes were used as immunogen to generate the CD35 antibody (Hogg et al, 1984).
Protein A or G purified
RUO
1378
Human, Monkey
Purified
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