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  6. CD365 (Tim-1) Monoclonal Antibody (RMT1-4), eBioscience™, Invitrogen™

CD365 (Tim-1) Monoclonal Antibody (RMT1-4), eBioscience™, Invitrogen™

Product Code. 17108505
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10 mg
100 μg
2 mg
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10mg
2mg
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17108505 10 mg 10mg
15297517 100 μg 100µg
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Product Code. 17108505 Supplier Affymetrix eBioscience Supplier No. 14586195

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Description

Rat Monoclonal Antibody

The RMT1-4 MAb reacts with mouse CD365 (also known as TIM1 and HAVCR1) and is a member of the T cell immunoglobulin domain, mucin-like domain (TIM) gene family. CD365 has been found on activated CD4+ T cells, mast cells, and a subset of B cells. CD365 is involved in renal injury, tissue homeostasis, and T cell costimulation. CD365 promotes the differentiation of Th2 cells and the production of IL-4. CD365 can bind several ligands, including Hepatitis A virus, phosphatidylserine, TIM4, IgA, as well as itself. CD365 and TIM4 can mediate uptake of apoptotic cells through recognition of phosphatidylserine. CD365, as well as the other TIM family members, are associated with susceptibility to atopic and autoimmune diseases. In humans, certain polymorphic variants of CD365 are strongly associated with protection against atopy, and this association occurs only in individuals who have had past infection with hepatitis A virus (HAV).

CD365 (Tim-1) Monoclonal antibody specifically detects CD365 (Tim-1) in Mouse samples. It is validated for Flow Cytometry
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD365 (Tim-1)
Applications Flow Cytometry
Classification Monoclonal
Clone RMT1-4
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene Havcr1
Gene Accession No. Q5QNS5
Gene Alias AI503787; CD365; HAVCR; Havcr1; HAVCR-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1
Host Species Rat
Purification Method Affinity chromatography
Quantity 10 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171283
Target Species Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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