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CD39 Monoclonal Antibody (eBioA1 (A1)), Super Bright™ 436, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

€ 161.00 - € 362.00

Specifications

Antigen CD39
Clone eBioA1 (A1)
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Product Code Brand Quantity Price Quantity & Availability  
15732486
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Affymetrix eBioscience
62-0399-42
100 Tests
€ 362.00
Pack of 100
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15722486
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Affymetrix eBioscience
62-0399-41
25 Tests This item is currently unavailable or has been discontinued.
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Description

Description

The eBioA1 monoclonal antibody reacts with human CD39 also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1) or NTPDase. CD39 is an integral membrane protein with two transmembrane domains and exists as a homotetramer. It is the most prominent ectoenzyme of the immune system. The function of CD39 is to effectively remove toxic extracellular ATP by converting it to ADP or AMP. CD39 is thought to work together with CD73 to hydrolyze ATP and has been well characterized on Langerhans cells. Expression of CD39 was originally identified on activated lymphocytes. Expression is also found on a subset of T cells, B cells and dendritic cells as well as weak staining on monocytes and granulocytes. Recently, CD39 and CD73 have been found on regulatory T cells (Treg). Expression of CD39 on Treg may facilitate their entry into inflamed areas where high levels of ATP are present. Expression of CD39 on Foxp3+CD4+ cells ranges from 25-45%. This eBioA1 (A1) antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Super Bright 436 can be excited with the violet laser line (405 nm) and emits at 436 nm. We recommend using a 450/50 bandpass filter, or equivalent.

CD39 Monoclonal antibody specifically detects CD39 in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD39
5 μL/Test
Monoclonal
Liquid
RUO
P49961
ENTPD1
Primary
4° C, store in dark, DO NOT FREEZE!
ENTPD1
eBioA1 (A1)
Flow Cytometry
Super Bright 436
Mouse
Human
953
IgG1 κ
Affinity chromatography
Antibody
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