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CD40 Mouse anti-Human, APC, Clone: 5C3, BD
Mouse Monoclonal Antibody
€ 60.31 - € 246.84
Specifications
| Antigen | CD40 |
|---|---|
| Clone | 5C3 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Conjugate | APC |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15831399
|
BD Biosciences
561848 |
25 Tests |
 € 60.40 € 60.31 / Each Save € 0.09 0.15% Off |
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|
15808298
|
BD Biosciences
555591 |
100 Tests |
€ 260.00 € 246.84 / Each Save € 13.16 5% Off |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
This 5C3 monoclonal antibody specifically binds to CD40, a 45-48 kDa type I integral membrane glycoprotein. CD40 is expressed on B lymphocytes, but is not expressed on terminally differentiated B cells. CD40 is also expressed by endothelial cells, basal epithelial cells and some epithelial cell carcinomas, follicular dendritic cells, macrophages, fibroblasts, keratinocytes, and CD34+ hematopoietic progenitor cells. This antibody is useful for studying the roles played by CD40 in B-cell growth, proliferation, and differentiation including immunoglobulin isotype switching. Anti-CD40 antibodies have been reported to stimulate B-cell proliferation when costimulated with anti-µ, anti-CD20 antibodies or with phorbol esters. 5C3 is capable of inducing B-cell proliferation when presented with IL-4.
This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Specifications
| CD40 | |
| Flow Cytometry | |
| APC | |
| RUO | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| 5C3 | |
| Monoclonal | |
| Mouse | |
| Human | |
| IgG1 κ | |
| Affinity Purified |
For Research Use Only.
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