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  6. CD41a Mouse anti-Human, APC, Clone: HIP8, BD

CD41a Mouse anti-Human, APC, Clone: HIP8, BD

Mouse Monoclonal Antibody

€ 61.29 - € 314.00

Specifications

Antigen CD41a
Clone HIP8
Applications Flow Cytometry
Classification Monoclonal
Conjugate APC
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BD Biosciences
561852 		25 Tests
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BD Biosciences
559777 		100 Tests
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Description

Description

The HIP8 monoclonal antibody specifically binds to the α-chain of CD41. CD41 is also known as Integrin αIIb or Platelet GPIIb. The calcium-dependent complex of CD41 and CD61 (β3 integrin or GPIIIa) is normally expressed on platelets and megakaryocytes. The CD41/CD61 complex is the receptor for fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation. CD41 (clone HIP8) completely inhibits ADP-, epinephrine-, and collagen-induced platelet activation, and partially inhibits ristocetin- and thrombin-induced platelet activation. This antibody is useful in the morphological and physiological studies of platelets and megakaryocytes.

Specifications

Specifications

CD41a
Flow Cytometry
APC
RUO
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
IgG1 κ
Affinity Purified
HIP8
Monoclonal
Mouse
Human
Purified platelet membrane glycoproteins
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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