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CD43/Sialophorin Antibody (SPN/1094), Allophycocyanin/Cy7, Novus Biologicals™
Mouse Monoclonal Antibody
Brand: Novus Biologicals NBP2-47880APCCY7
This item is not returnable.
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Description
CD43/Sialophorin Monoclonal specifically detects CD43/Sialophorin in Human samples. It is validated for Flow Cytometry.
Specifications
| CD43/Sialophorin | |
| Monoclonal | |
| APC-Cyanine7 | |
| PBS with 0.05% Sodium Azide | |
| SPN | |
| Recombinant full-length human CD43/Sialophorin protein (Uniprot: P16150) | |
| 0.1 mL | |
| Primary | |
| It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma. | |
| Store at 4°C in the dark. Do not freeze. |
| Flow Cytometry | |
| SPN/1094 | |
| Flow Cytometry | |
| CD43 antigen, CD43), Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein, Sialophorin, sialophorin (gpL115, leukosialin, CD43) | |
| Mouse | |
| Protein A or G purified | |
| B Cell Development and Differentiation Markers, Immunology | |
| 6693.0 | |
| Human | |
| IgG1 κ |
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