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Invitrogen™ CD45RC Monoclonal Antibody (C455.1F), Biotin
Rat Monoclonal Antibody
Brand: Invitrogen™ MA528673
This item is not returnable.
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Description
CD45RC Monoclonal Antibody for Flow
CD45RC (PTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. It acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, the second affects the substrate specificity of the first. Upon T-cell activation, CD45RC recruits and dephosphorylates SKAP1 and FYN. Mutations of the gene can result in severe combined immunodeficiency and multiple sclerosis.
Specifications
| CD45RC | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with proprietary stabilizer and <0.1% sodium azide; pH 7.4 | |
| P06800 | |
| Ptprc | |
| purified | |
| RUO | |
| 19264 | |
| 4°C | |
| Liquid |
| Flow Cytometry | |
| C455.1F | |
| Biotin | |
| Ptprc | |
| B220; CD45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; LCA; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen | |
| Rat | |
| 1 mL | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2a κ |
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