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Invitrogen™ CD46 Recombinant Rabbit Monoclonal Antibody (6D2A4)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA535207
This item is not returnable.
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Description
Immunogen sequence: MEPPGRRECP FPSWRFPGLL LAAMVLLLYS FSDACEEPPT FEAMELIGKP KPYYEIGERV DYKCKKGYFY IPPLATHTIC DRNHTWLPVS DDACYRETCP.
CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.
Specifications
| CD46 | |
| Recombinant Monoclonal | |
| 0.5 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P15529 | |
| CD46 | |
| A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CD46 (P15529). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| ELISA, Immunohistochemistry (Paraffin), Western Blot | |
| 6D2A4 | |
| Unconjugated | |
| CD46 | |
| AHUS2; antigen identified by monoclonal antibody TRA-2-10; brain microvascular membrane cofactor; brain microvascular membrane cofactor protein CD46; Cd46; CD46 antigen, complement regulatory protein; CD46 complement regulatory protein; CD46 molecule; CD46 molecule, complement regulatory protein; CD46 splice variant; complement membrane cofactor protein; complement regulatory protein; Mcp; MCP; complement activation regulator; measles virus receptor; membrane cofactor protein; membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen); membrane cofactor protein variant 10; membrane cofactor protein variant 7; membrane cofactor protein variant 8; membrane cofactor protein variant 9; MGC26544; MIC10; soluble membrane cofactor protein variant 11; soluble membrane cofactor protein variant 12; soluble membrane cofactor protein variant 13; TLX; TRA2.10; trophoblast leucocyte common antigen; trophoblast leukocyte common antigen; trophoblast-lymphocyte cross-reactive antigen | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 4179 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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