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  6. CD49f Rat anti-Human, PerCP-Cy5.5, Clone: GoH3, BD

CD49f Rat anti-Human, PerCP-Cy5.5, Clone: GoH3, BD

Product Code. 15811979
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15811979 25 Tests Each
15811959 100 Tests Each
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Product Code. 15811979 Supplier BD Biosciences Supplier No. 562495

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Description

Rat Monoclonal Antibody

The GoH3 monoclonal antibody specifically binds to CD49f which is also known as integrin α6 chain. CD49f is a ∽150 kDa type I transmembrane glycoprotein that belongs to the integrin alpha chain family of extracellular matrix and cell adhesion receptors. The integrin α6 subunit associates with the integrin β1 chain (CD29) to form VLA-6 and with the integrin β4 chain (CD104) to form the integrin α6β4 complex, also known as the laminin and kalinin receptor. CD49f is expressed mainly on T cells, monocytes, platelets, epithelial cells, endothelial cells, perineural cells, and trophoblasts of placenta. GoH3 recognizes an extracellular epitope of integrin α6 on human, mouse and bovine cells. GoH3 has been reported to block the binding of integrin α6 to laminin P1 and E8 fragments.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD49f
Applications Flow Cytometry
Classification Monoclonal
Clone GoH3
Conjugate PerCP-Cyanine5.5
Description ITGA6; IThe GoH3 monoclonal ntegrin alpha-6; Integrin α6 chain; VLA-6; ITA6
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse mammary tumor cells
Purification Method Affinity Purified
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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For Research Use Only.

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