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Invitrogen™ CD53 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA551130

Product Code. 15625055

  • € 516.00 / 100µL

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Description

Description

CD53 / TSPAN-25 Polyclonal Antibody detects endogenous levels of CD53 / TSPAN-25 protein.

CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage. This molecule has been reported to form complexes with other leukocyte surface proteins such as CD2, CD19, CD21, MHC II, VLA-4 or tetraspanins CD37, CD81 and CD82, thus probably modulating various signaling processes. CD53 is involved in radioresistancy of tumor cells and its triggering has anti-apoptotic effect. In thymus, CD53 is up-regulated in response to positive selection signals during T cell development, and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide, whereas stimulation of neutrophils results in down-regulation of CD53 expression.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD53
Polyclonal
Unconjugated
Cd53
AI323659; antigen MOX44 identified by monoclonal antibody MRC-OX44; Cd53; CD53 antigen; CD53 glycoprotein; CD53 molecule; CD53 tetraspan antigen; cell surface antigen; cell surface glycoprotein CD53; Leukocyte antigen MRC OX-44; leukocyte surface antigen CD53; MOX44; OX44; Ox-44; tetraspanin-25; transmembrane glycoprotein; TSPAN25; tspan-25
Rabbit
Antigen affinity chromatography
RUO
12508, 24251, 963
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Western Blot
1 mg/mL
PBS with 50% glycerol, 0.5% BSA and 0.02% sodium azide; pH 7.4
P19397, P24485, Q61451
Cd53
Synthesized peptide derived from the Internal region of human CD53.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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