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Invitrogen™ CD68 Recombinant Mouse Monoclonal Antibody (PDM0-13)
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Product Code. 17909212
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Quantity:
100 μL
Unit Size:
100µL
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17909212 100 μL 100µL
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Product Code. 17909212 Supplier Invitrogen™ Supplier No. MA550651

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Description

Mouse Recombinant Monoclonal Antibody

Positive control: Human spleen tissue, human diffuse large B-cell lymphoma tissue, human tonsil tissue, human liver tissue, THP-1, human non-small cell lung cancer, human cervical cancer. Predicted band size: 37 kDa Subcellular Location: Cell membrane Endosome membrane, Lysosome membrane.

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD68
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Immunocytochemistry, Multiplex Immunohistochemistry
Classification Recombinant Monoclonal
Clone PDM0-13
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Cd68
Gene Accession No. P34810
Gene Alias CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen
Gene Symbols Cd68
Host Species Mouse
Immunogen Recombinant protein within Human CD68 aa 1-354.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 968
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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