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  6. CD69 Hamster anti-Mouse, PE-Cy7, Clone: H1.2F3, BD

CD69 Hamster anti-Mouse, PE-Cy7, Clone: H1.2F3, BD

Product Code. 15846888
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0.1 mg
25 μg
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15846888 0.1 mg Each
15851479 25 μg Each
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Product Code. 15846888 Supplier BD Biosciences Supplier No. 552879

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Description

Hamster Monoclonal Antibody

The H1.2F3 monoclonal antibody specifically binds to CD69 (Very Early Activation antigen), an 85 kDa disulfide-linked homodimer of differentially glycosylated subunits. CD69 is a C-type lectin, most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules. Its expression is rapidly induced upon activation of lymphocytes (T, B, NK, and NK-T cells), neutrophils, and macrophages. CD69 is expressed also on thymocytes that are undergoing positive selection; its role in that process is unclear. H1.2F3 mAb augments PMA-induced T-cell stimulation and IFN-γ-induced macrophage stimulation. IL-2-activated NK cells express CD69, and H1.2F3 mAb induces redirected lysis of FcR-bearing target cells by NK cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD69
Applications Flow Cytometry
Classification Monoclonal
Clone H1.2F3
Concentration 0.2mg/mL
Conjugate PE-Cyanine7
Description VEA; Very Early Activation Antigen; AIM; Activation Induced Molecule
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Hamster
Immunogen Mouse Dendritic Epidermal T Cell Line Y245
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1
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For Research Use Only.

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