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CD71 (Transferrin Receptor) Mouse anti-Human, Functional Grade, Clone: OKT9 (OKT-9), eBioscience™
Mouse Monoclonal Antibody
Merk: Affymetrix eBioscience 16-0719-85
Overige gegevens : Gewicht : 0.01000kg
Beschrijving
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregcy, irritable bowel syndrome and in HIV patients.Specificatie
CD71 (Transferrin Receptor) | |
Monoclonal | |
1 mg/mL | |
PBS with no preservative; pH 7.2 | |
P02786 | |
CD71, T9, TFR, TFR1, TR, TRFR, p90, transferrin receptor protein 1 | |
Mouse | |
Affinity chromatography | |
RUO | |
Antibody | |
Monoclonal | |
Human |
Control, Flow Cytometry, Functional Assay | |
OKT9 (OKT-9) | |
Functional Grade | |
TFRC | |
Liquid | |
TFRC | |
IgG1, kappa | |
500 μg | |
4° C | |
Primary | |
7037 |
For Research Use Only.