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Invitrogen™ CD82 Monoclonal Antibody (07)

Beschreibung
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human CD82/KAI-1.
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Spezifikation
Spezifikation
| Antigen | CD82 |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Monoclonal |
| Clone | 07 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with no preservative |
| Gene | CD82 |
| Gene Accession No. | P27701 |
| Gene Alias | 4F9; AA682076; AL023070; C33; C33 antigen; Cd82; CD82 antigen; CD82 antigen (R2 leukocyte antigen antigen detected by monoclonal and antibody IA4)); CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)); CD82 molecule; GR15; IA4; Inducible membrane protein R2; KAI1; Kangai 1 (suppression of tumerigenicity 6 prostate) CD82 antigen; kangai 1 (suppression of tumorigenicity 6), prostate; kangai 1 (suppression of tumorigenicity 6, prostate); Kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)); metastasis suppressor Kangai-1; Metastasis suppressor Kangai-1 homolog; R2; SAR2; ST6; Suppressor of tumorigenicity 6 protein; Tetraspanin-27; Tspan27; tspan-27 |
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