missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Description
Immunogen sequence: NSHVVYQLLS PEPEDGVEGR AFQVDPTSGS VTLGVLPLRA GQNILLLVLA MDLAGAEGGF SSTCEVEVAV TDINDHAPEF ITSQIGPISL PEDVEPGTLV AMLTAIDADL EPAFRLMDFA IERGDTEGTF GLDWEPDS Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 76%.
The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-16, also known as Ksp-Cadherin, is a type I membrane protein which is kidney-specific. Cadherin-16 is expressed exclusively in the basolateral membrane of renal tubular epithelial cells. The human Ksp-cadherin gene (Cadherin-16) maps to chromosome 16q21-proximal 16q22. The mouse Ksp-cadherin gene was localized to a highly syntenic region of distal Chromosome 8.
Specifications
Specifications
| Antigen | CDH16 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | CDH16 |
| Gene Accession No. | O75309 |
| Gene Alias | Cadherin; cadherin 16; cadherin 16, KSP-cadherin; cadherin-16; Cadherin-16 (CDH16); CDH 16; CDH16; Kidney-specific cadherin; KSP-cadherin; Ksp-cadherin antibody; UNQ695/PRO1340 |
| Gene Symbols | CDH16 |
| Show More |
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?
