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Invitrogen™ CDK2AP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA568392

Product Code. 15863224

  • € 520.00 / 100µL

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Description

Description

CDK2AP1 Polyclonal Antibody for IHC (P)

The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CDK2AP1
Polyclonal
Unconjugated
CDK2AP1
Apc10; CDK2 (cyclin-dependent kinase 2)-associated protein 1; Cdk2ap1; CDK2-associated protein 1; CDKAP1; cyclin dependent kinase 2 associated protein 1; cyclin-dependent kinase 2 associated protein 1; cyclin-dependent kinase 2-associated protein 1; Deleted in oral cancer 1; Deleted in oral cancer-1; Doc1; doc-1; DORC1; p12; p12DOC-1; Putative oral cancer suppressor; ST19
Rabbit
Antigen affinity chromatography
RUO
8099
-20°C
Liquid
Immunohistochemistry (Paraffin)
0.8 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
O14519
CDK2AP1
Full length Fusion protein of human CDK2AP1.
100 μL
Primary
Human
Antibody
IgG
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