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  4. Invitrogen™ Human CDKL5, GST Tag Recombinant Protein

Invitrogen™ Human CDKL5, GST Tag Recombinant Protein

Product Code. 15990273
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Quantity:
1 mg
10 μg
100 μg
Unit Size:
100µg
10µg
1mg
This item is not returnable. View return policy

Product Code. 15990273

Brand: Invitrogen™ A30493

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This item is not returnable. View return policy

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This CDKL5 recombinant human protein (1-498) was expressed in insect cells. CDKL5 recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service. Validated for use with the Z'-LYTE™ assay Available in multiple pack sizes for convenient use Also available in our SelectScreen Kinase Profiling Service Protein Form: Recombinant, Active, Catalytic.

CDKL5 serine/threonine kinase (STK9) is associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome and Rett syndrome (RTT). CDKL5 can control nuclear speckle morphology by regulating the phosphorylation state of splicing regulatory proteins, and may be involved indirectly in pre-mRNA processing by controlling splicing factor dynamics. The mutations in CDKL5 are major cause of infantile spasms and early epileptic seizures in female patients, and of a later intractable seizure disorder.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O76039
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50mM tris HCl with 0.25mM DTT, 25% glycerol, 0.1mM PMSF, 0.1mM EDTA, 150mM NaCl, 10mM glutathione and no preservative; pH 7.5
Gene ID (Entrez) 6792
Molecular Weight (g/mol) 82.7 kDa
Name Human CDKL5, GST Tag
pH Range 7.5
Purification Method Purified
Quantity 10 μg
Storage Requirements -80°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias BC038161; Cdkl5; CFAP247; cyclin dependent kinase 5 transcript; cyclin dependent kinase like 5; cyclin-dependent kinase-like 5; EIEE2; ISSX; RP1-245G19.3; serine/threonine kinase 9; serine/threonine-protein kinase 9; STK9
Common Name CDKL5
Gene Symbol CDKL5
KinaseFamily CDKs and CHKs
Protein Length 1-498
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence 1-498
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Shipping Condition Dry Ice
Expression System Insect cells
Protein Family Kinases & Inhibitors
Protein Form Recombinant, Active, Catalytic
Form Liquid
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