missing translation for 'onlineSavingsMsg'
Learn More
Learn More
CDKN2A (p16INK4a) Monoclonal Antibody (OTI9A2), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA805096
This item is not returnable.
View return policy
Description
In humans, the multiple tumor suppressor 1 locus (MTS1) encodes two unrelated genes, p16INK4a and p19ARF. Although both act as cell proliferation inhibitors, their mechanisms of action are different. p19ARF works as part of a p53-dependent pathway to counter uncontrolled proliferation and oncogenic signals. Mice lacking the p19ARF gene rapidly develop a broad spectrum of tumors. This result indicates that p19ARF is an important tumor suppressor. In addition, p19ARF helps prevent transforming signals from various onocoproteins via the p53 regulatory loop. These studies and others display the importance of p19ARF in cell cycle control and tumor suppression.Specifications
| CDKN2A (p16INK4a) | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| Q8N726 | |
| CDKN2A | |
| Full length human recombit protein of human CDKN2A produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Western Blot | |
| OTI9A2 | |
| Unconjugated | |
| CDKN2A | |
| ARF, CDK4I, CDKN2, CMM2, INK4, INK4A, MLM, MTS-1, MTS1, P14, P14ARF, P16, P16-INK4A, P16INK4, P16INK4A, P19, P19ARF, TP16 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 1029 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
Correzione del contenuto del prodotto
Il programma Encompass di Fisher Scientific offre articoli che non fanno parte del nostro portafoglio di distribuzione. Questi prodotti in genere non hanno immagini o descrizioni dettagliate. Tuttavia, ci impegniamo a migliorare la vostra esperienza di acquisto. Si prega di utilizzare il modulo sottostante per fornire un feedback relativo al contenuto di questo prodotto.
Titolo del prodotto
Individuate un'opportunità di miglioramento?Condividi una correzione di contenuto