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Invitrogen™ CDKN2B (Isoform 2) Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA5142832
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Description
Additional Information: This antibody is expected to recognize isoform 2 (NP_511042.1) only. This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008].
Specifications
| CDKN2B (Isoform 2) | |
| Polyclonal | |
| Unconjugated | |
| CDKN2B | |
| CDKN2B | |
| Peptide with sequence C-RQGARERGARP. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Western Blot | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| P42772 | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 1030 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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